Figure 1.

LocusZoom plot highlighting the top hit (rs12051168) of the single-variant whole genome sequencing family-based association test analysis. The plot shows the covariate-unadjusted results with −log¹⁰ P values (y-axis 1), recombination rates (y-axis 2), and genome-wide significance threshold (dashed line) for SNPs (rs12051168 as highlighted by the red dashed line, rs12919905 adjacent to rs12051168 as highlighted by the gray dashed line) in the CRISPLD2 gene on chromosome 16. cM = centimorgan; Mb = Megabase; SNP = single-nucleotide polymorphism.