Table II.
Logistic regression modelling of enrollment factors influencing EIG overall and food-specific nonadherence
| EIG overall nonadherence |
EIG-specific food nonadherence |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Peanut |
Egg |
Milk |
Sesame |
Fish |
Wheat |
|||||||||
| OR | P value | OR | P value | OR | P value | OR | P value | OR | P value | OR | P value | OR | P value | |
| Ethnicity (nonwhite) | 2.19 (1.13-4.25) | .02 | 2.16 (1.20-3.91) | .01 | 1.67 (0.90-3.10) | .11 | 1.67 (0.79-3.50) | .18 | 1.68 (0.93-3.02) | .08 | 2.06 (1.14-3.73) | .02 | 1.68 (0.90-3.14) | .10 |
| Visible eczema at enrollment (continuous SCORAD score) | 1.02 (0.99-1.06) | .16 | 1.02 (0.99-1.05) | .21 | 1.02 (0.99-1.05) | .27 | 1.01 (0.98-1.05) | .41 | 1.04 (1.01-1.07) | .02 | 1.04 (1.01-1.07) | .01 | 1.01 (0.98-1.04) | .43 |
| QOL psychological domain (< mean) | 1.51 (1.02-2.22) | .04 | 1.17 (0.79-1.72) | .44 | 1.21 (0.82-1.77) | .34 | 0.99 (0.57-1.69) | .96 | 1.06 (0.72-1.54) | .77 | 1.02 (0.70-1.50) | .91 | 1.42 (0.97-2.07) | .07 |
| Food-specific IgE at enrollment∗ (≥0.1 kU/L) | 0.88 (0.48-1.60) | .68 | 1.18 (0.39-3.59) | .77 | 2.32 (0.85-6.31) | .10 | 1.33 (0.39-4.56) | .65 | 0.94 (0.28-3.14) | .92 | — | — | 0.47 (0.18-1.24) | .13 |
| Maternal age (≥ median, 33 y) | 1.59 (1.08-2.33) | .02 | 1.85 (1.25-2.76) | .002 | 2.32 (1.58-3.41) | <.001 | 1.85 (1.04-3.30) | .04 | 1.27 (0.87-1.85) | .22 | 1.54 (1.04-2.27) | .03 | 1.28 (0.88-1.87) | .19 |
| Nocturnal sleep duration at enrollment (h) | 0.92 (0.79-1.06) | .23 | 0.88 (0.76-1.01) | .07 | 0.91 (0.79-1.04) | .17 | 0.94 (0.78-1.14) | .54 | 0.95 (0.83-1.09) | .47 | 0.92 (0.80-1.06) | .26 | 0.90 (0.79-1.04) | .15 |
| Nighttime awakenings at enrollment (no. of awakenings) | 1.14 (0.97-1.34) | .11 | 1.06 (0.91-1.25) | .44 | 1.18 (1.01-1.39) | .04 | 1.00 (0.81-1.25) | .98 | 1.09 (0.93-1.27) | .31 | 1.13 (0.97-1.32) | .13 | 1.10 (0.93-1.29) | .26 |
| Parent-reported sleep problem at enrollment (none/small problem/very serious problem) | 1.11 (0.73-1.67) | .63 | 1.27 (0.85-1.90) | .25 | 0.87 (0.58-1.30) | .49 | 1.21 (0.69-2.10) | .50 | 0.95 (0.64-1.42) | .80 | 0.84 (0.56-1.26) | .40 | 0.98 (0.66-1.46) | .92 |
OR, Odds ratio.
∗
Food-specific IgE (≥0.1 kU/L) to any food for EIG overall nonadherence and to the specific food for individual food-specific nonadherence. If sensitization status was included in the model based on skin prick test response at enrollment, the result was statistically nonsignificant for overall nonadherence and food-specific nonadherence to any individual food, with the exception of milk (positive milk skin prick test response: OR, 13.8; 95% CI, 1.68-112; P = .01). For each outcome, all the variables listed were included in the same logistic regression model.