(A) Western blot analysis of Prp19-HA protein levels in wild-type and eaf3Δ cells. Pgk1 is a loading control.
(B) Occupancy of Prp19-HA on ICGs HPC2 (left) and RAD14 (right) relative to a non-transcribed region (NTR) on Chr. V in wild-type (light gray bars) and eaf3Δ (medium gray bars).
(C) Occupancy of Prp19-HA on ICG ECM33 relative to a NTR on Chr. V. in wild-type and eaf3Δ cells. Bars represent the average of at least 3 biological replicates. Error bars represent the SEM. p values were determined by 2-tailed unpaired t test. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001.