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. Author manuscript; available in PMC: 2019 Dec 11.
Published in final edited form as: Cell Rep. 2019 Jun 25;27(13):3760–3769.e4. doi: 10.1016/j.celrep.2019.05.100

Figure 5. Eaf3 Recognizes H3K36 Methylation to Regulate Pre-mRNA Splicing.

Figure 5.

Eaf3 recruits Prp45 and the nineteen complex (NTC) to the precatalytic complex B to promote spliceosome activation. The putative NTC and Prp45 interaction with the spliceosome prior to U1 and U4 snRNP release may be transient (indicated by dashed lines).