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. 2019 Dec 10;13:66. doi: 10.1186/s40246-019-0252-0

Fig. 1.

Fig. 1

LRF/ZBTB7A regulates hematopoiesis and lymphoid development. LRF/ZBTB7A contribution in specific stages of cell differentiation is indicated. Abbreviations: HSC, hematopoietic stem cell; CMP, common myeloid progenitors; BFU-E, burst-forming unit-erythroid; CFU-E, colony-forming unit-erythroid; ProE, proerythroblasts; BasoE, basophilic erythroblasts; PolyE, polychromatophilic erythroblasts; OrthoE, orthochromatic erythroblasts; RBC, matured erythrocytes; CLP, common lymphoid progenitors; ProB, progenitor B cell; PreB, precursor B cell; DN T cell, double negative or CD4-/8- negative; DP T cell, double positive or CD4+/8+ positive; CD4+ single positive expressing Thpok (T-helper inducing POZ/Krüppel-like factor); CD8+ single positive expressing the Runx3; FOB, follicular B cells; MZB, marginal zone B cells; GCΒ, germinal center B cells