Table 3.
Comparison of SSc subsets by univariable analyses
| Dependent variable | Independent variable | Univariable analysis | ||
|---|---|---|---|---|
| B (95% CI) | β | p value | ||
| DXA L2–4 BMD | Age | − 0.006 (− 0.010 to − 0.002) | − 0.427 | 0.005 |
| Age at dg. | − 0.007 (− 0.013 to − 0.001) | − 0.397 | 0.017 | |
| BMI | 0.014 (0.005 to 0.022) | 0.471 | 0.002 | |
| DXA FN BMD | Age | − 0.004 (− 0.007 to 0) | − 0.324 | 0.027 |
| BMI | 0.009 (0.002 to 0.015) | 0.346 | 0.027 | |
| Female vs. male | − 0.131 (− 0.226 to − 0.036) | − 0.392 | 0.008 | |
| pQCT total density | Female vs. male | − 69.529 (− 115.229 to − 23.826) | − 0.382 | 0.004 |
| Pulmonary manifestation | − 51.367 (− 95.655 to − 7.078) | − 0.423 | 0.024 | |
| Digital ulcer | − 56.903 (− 97.273 to − 16.532) | − 0.402 | 0.007 | |
| anti Scl70+ | − 50.693 (− 91.123 to − 10.263) | − 0.313 | 0.015 | |
| pQCT trabecular density | Pulmonary manifestation | − 48.234 (− 93.028 to − 3.440) | − 0.318 | 0.035 |
| ACA+ | 91.292 (47.628 to 134.956) | 0.546 | 0.001 | |
| pQCT cortical density | Female vs. male | − 120.46 (− 193.899 to − 47.021) | − 0.455 | 0.002 |
| Pulmonary manifestation | − 82.502 (− 147.791 to − 17.212) | − 0.326 | 0.015 | |
| Digital ulcer | − 92.848 (− 146.016 to − 39.680) | − 0.450 | 0.001 | |
| anti Scl70+ | − 94.645 (− 161.926 to − 27.365) | − 0.401 | 0.007 | |
Abbreviations: ACA anti-centromere antibody, BMD bone mineral density, DXA dual-energy X-ray absorptiometry, FN femoral neck, pQCT peripheral quantitative computed tomography. See text for further explanations