. Author manuscript; available in PMC: 2020 Nov 12.

Published in final edited form as: J Am Coll Cardiol. 2019 Nov 12;74(19):2333–2345. doi: 10.1016/j.jacc.2019.08.1057

Table 3.

Demographic differences amongst HCM morphologies.

	Isolated basal septal	Reverse curvature	Apical	Concentric	Apical aneurysm	Other	Overall p value
Variable	N=1199	N=1063	N=224	N=36	N=79	N=33
Age (years)	51.6±10.3^*^§	47.1±12.0^†	51.3±9.7^§	50.0±11.3	49.7±11.4	45.8±13.7	< 0.001
BMI (kg/m²)	29.8±5.5^*	28.6±5.6	28.9±4.8	33.5±8.1^‡^*^†^{^}	28.9±5.4	28.6±6.2	< 0.001
<Male	839 (70.1)	758 (71.5)	175 (78.1)	30 (83.3)	47 (59.5)	22 (66.7)	0.014
Minority	121 (10.1)^*^†	179 (16.9)^†	75 (33.5)	11 (30.6)^‡	22 (27.9)^‡	4 (12.1)	< 0.001
Maximal wall thickness (mm)	17.4±3.6 ^*	20.0±5.2^†^§	17.1±4.5	22.2±6.3^‡^†^§	19.6±6.0^‡^†	16.7±3.5	< 0.001
LVOT gradient ≥ 30mm Hg	279 (30.4)^*	164 (20.8)^†	7 (5.1)^‡	8 (33.3)^†	13 (23.6)^†	2 (7.4)	< 0.001
Arrythmias	161 (13.5)^*^†	224 (21.3)	51 (22.9)	6 (17.1)	28 (35.4)^‡^*	6 (18.2)	< 0.001
LVEF < 55%	145 (12.4)	168 (16.3)	20 (9.1)	11 (30.6)^‡^†	13 (16.7)	4 (12.1)	0.002
HTN	504 (42.2)^*	309 (29.3)	81 (36.3)	16 (44.4)	31 (39.2)	14 (42.4)	< 0.001

Data are mean ± 1 standard deviation for continuous variables; n (%) for categorical variables.

Percentages based on non-missing values.

For each variable, correction for Type I error was set at < 0.0055 (0.05/9). If the overall p value was <0.0055, pairwise comparisons between morphology categories were made at p < 0.0055.

p<0.0055 vs. reverse curvature

^†

p<0.0055 vs. apical

^{^}

p<0.0055 vs. apical aneurysm

^§

p<0.0055 vs. other

^‡

p<0.0055 vs. isolated basal septal