. Author manuscript; available in PMC: 2020 Nov 12.

Published in final edited form as: J Am Coll Cardiol. 2019 Nov 12;74(19):2333–2345. doi: 10.1016/j.jacc.2019.08.1057

Table 7.

Demographic and clinical differences by genetic category.

Variable	Sarcomere mutation (+) % (n)	Sarcomere mutation (−) % (n)	Unadjusted p value	Bonferroni adjusted p value
Age (years)	46.2 ± 12.0	51.3 ± 10.4	< 0.001	< 0.001
BMI (kg/m²)	28.2 ± 5.4	29.8 ± 5.6	< 0.001	< 0.001
Male	65.1 (611)	75.3 (1260)	< 0.001	< 0.001
Minority	28.4 (116)	37.4 (823)	0.001	0.009
Family history of HCM	54.7 (511)	22.3 (371)	< 0.001	< 0.001
LVOT gradient ≥30mm Hg	19.0 (130)	26.8 (335)	< 0.001	< 0.001
Arrhythmias	38.1 (185)	35.4 (749)	0.255	1.000
Hypertension	21.3 (199)	45.1 (752)	< 0.001	< 0.001
LVEF < 55%	14.2 (126)	14.2 (227)	0.983	1.000

Data are mean ± 1 Standard Deviation for continuous variables and n (%) for dichotomous variables. A Bonferroni correction for multiplicity was made for 9 variables for nominal Type I error rate of 0.05: p < 0.0055 (0.05/9).