Table 2.
Wnt/β-catenin pathway-associated long noncoding RNAs in EOC
| Targets | Expression in EOC | Effects on EOC | Effects on β-catenin activity | Reference | |
|---|---|---|---|---|---|
| Long noncoding RNAs | |||||
| CCAT2 | ND* | Increased | Promote EMT | Activate | [120] |
| SNHG20 | Inactivate GSK3b | Increased | Promote proliferation and inhibit apoptosis | Activate | [121] |
| MALAT1 | Increase DVL2 and β-catenin | Increased | Promote proliferation, migration and inhibit apoptosis | Activate | [122] |
| Linc-ROR | ND | Increased | Promote proliferation, migration and invasion through EMT | Activate | [123] |
| HOTAIR | ND | Increased | Promote proliferation and chemoresistance | Activate | [124] |
| HOXD-AS1 |
miR-133a-3p, miR-186-5p |
Increased | Promote cell proliferation and invasion | Activate | [113] |
| circRNAs | |||||
| Circ-ITCH | miR-145 | Decreased | Inhibit OC cells proliferation, migration and invasion | Suppress | [125] |
| Circ_0061140 | miR-370 | Increased | Promote cell proliferation and migration | Activate | [109] |
*ND, not determined