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. 2019 Dec 10;8:320. doi: 10.1186/s13643-019-1243-x

Table 13.

Other conditions

Author, year {refid} Search dates; # databases searched Funding source Nstudies Illness/condition Intervention/comparator* Outcomes Conclusions from data AMSTAR-2 rating
Huntley, 2000 [66] Inception to Dec 1999; 4 NR 1 Asthma

I: Plant-derived cannabinoids

C: Placebo

• Airway resistance (raw) Only one study included M
Singh, 2007 [77] Inception to Dec 2004; 6 Non-profit 4 Asthma

I: Plant-based cannabis

C: Placebo; isoproterenol; low-dose marijuana

• Pulmonary function test Reported SBS M
Snedecor, 2013 [70] To Jun 2011; 5 Industry 1 Diabetes

I: Plant-derived cannabinoids

C: placebo

• Peripheral NP (mean reduction in pain)

• Peripheral NP (mean probability of 30% pain reduction)

Unclear efficacy (not enough information provided by authors) L
Norton, 2017 [28] Inception–Feb 2016; 5 NR 3 Inflammatory bowel disease

I: Plant-based cannabis

C: No comparator (observational study)

N/A observational data N/A observational data CL
Langhorst, 2015 [44] Inception–Mar 12, 2014; 4 Non-profit 1 Inflammatory bowel disease (Crohn's, ulcerative colitis, IBS)

I: Plant-based cannabis

C: Placebo cigarettes (THC removed)

• Response rate

• QoL

• Remission rate

Only one study included M
CADTH, 2014 [81] Jan 1, 1982 to Aug 8 2014; 5 NR 4 Nausea and vomiting (non-chemotherapy-induced)

I: Synthetic cannabinoids

C: Metoclopramide

• Postoperative nausea and vomiting

• Patient rating of nausea and vomiting (VAS)

Only one study included L

CADTH Canadian Agency for Drugs and Technologies in Health, IBS irritable bowel syndrome, NR not reported, QoL quality of life, SBS study-by-study, VAS visual analog scale

*A colon indicates that there were separate analyses for each comparator