Median pH4 time for different omeprazole equivalents showing different doses of PPI given bid and 10 mg of vonoprazan given once daily in terms of relative effectiveness as adjuvants for improving the efficacy of a triple therapy containing amoxicillin. P, pantoprazole; R, rabeprazole; O, omeprazole; E, esomeprazole; L, lansoprazole. Arrow shows vonoprazan 10 mg