Table 2: Summary statistics for biomarkers levels in YWH (n=128).
Values are mean (standard deviation) unless otherwise noted.
| Biomarker | (n=128) |
|---|---|
| Macrophage Activation | |
| sCD14 (ng/mL) | 1468.04 (420.66) |
| sCD163 (ng/mL) | 548.40 (304.97) |
| CCL2 (pg/mL) | 209.54 (304.35) |
| GM-CSF (pg/mL) | 1.55 (2.42) |
| Below Limit of Detection (LOD 0.01 pg/mL)a | 53 (41.4%) |
| IL-1β(pg/mL) | 38.15 (116.63) |
| Below Limit of Detection (LOD 0.01 pg/mL)a | 33 (25.8%) |
| IL-6 (pg/mL) | 17.43 (74.66) |
| Below Limit of Detection (LOD 0.1 pg/mL)a | 26 (20.3%) |
| IL-8 (pg/mL) | 64.69 (291.50) |
| LPS (EU/mL) | 0.21 (0.08) |
| MMP-2 (ng/mL) | 195.64 (39.29) |
| TNFα (pg/mL) | 11.35 (25.71) |
| Vascular Inflammation | |
| sICAM-1 (ng/mL) | 215.07 (303.69) |
| sVCAM-1 (ng/mL) | 595.20 (238.83) |
| CRP (ng/mL) | 1424.01 (5517.78) |
| MPO (ng/mL) | 279.70 (270.26) |
| Lymphocyte Activation | |
| sCD27 (U/mL) | 57.39 (36.91) |
| IFNγ (pg/mL) | 20.23 (44.42) |
| Below Limit of Detection (LOD 0.1 pg/mL)a | 49 (38.3%) |
| IL-10 (pg/mL) | 8.25 (14.82) |
| Below Limit of Detection (LOD 0.1 pg/mL)a | 35 (27.3%) |
| sIL-2rα (pg/mL) | 67.91 (80.67) |
| Below Limit of Detection (LOD 0.1 pg/mL)a | 1 (0.8%) |
a
Frequency (percent)