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. 2019 Dec 6;9(24):191210. doi: 10.5696/2156-9614-9.24.191210

Table 1.

Reference Doses (RfD) in (mg/kg-day) and Cancer Slope Factors (CSF) for the Pathways

Heavy Metal Oral RfD Dermal RfD Inhalation RfD Oral CSF Dermal CSF Inhalation CSF References
Pb 3.60E-03 - - 8.50E-03 - 4.20E-02 34,35
Chromium (VI) 3.00E-03 - 3.00E-05 5.00E-01 - 4.10E+01 36,34
Cobalt 2.00E-02 5.70E-06 5.70E-06 - - 9.80E+00 36
Nickel 2.00E-02 5.60E-03 - - - - 34
Copper 0.037 0.037 - - - - 34,36
Zinc 3.00E-01 7.50E-02 - - - - 34,36

Abbreviations: RfD, reference dose; CSF, cancer slope factor