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. 2019 Dec 4;7:388. doi: 10.3389/fbioe.2019.00388

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Copyright © 2019 Zhu, Gao, Wang, Li, Shang, Wang, Guo, Zhou, Liu, Sun, Chen, Wang and Ning.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The levels of some methylation sites were differential in age-related cancer samples between m-age and chronological age. (A) Age different scores between chronological age and predicted m-age among 33 cancer types. (B) The relationship between chronological age and predicted m-age for all the 33 disease types. Compared to the chronological age group, the pink color indicates that the predicted m-age group was down-regulated, the blue color indicates that the predicted m-age group was up-regulated, and the gray color indicates that the predicted m-age group remained unchanged.