Figure 1.

Time-dependent images of the blood oxygen level-dependent signal in gray and white matter regions at rest.

The colored blocks indicate the correlation between white and corresponding gray matter regions. The shade of the color indicates the strength of the correlation, with darker colors having stronger correlations. The colormap (right) indicates colors corresponding to the magnitude and direction (positive or negative) of the correlation. Threshold is at the mean |correlation coefficient| > 0.4. (A–D) Normal cognition group (A), early mild cognitive impairment group (B), late mild cognitive impairment group (C), and Alzheimer’s disease group (D).