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. Author manuscript; available in PMC: 2019 Dec 11.
Published in final edited form as: Biochemistry. 2019 Nov 26;58(49):4970–4982. doi: 10.1021/acs.biochem.9b00878

Figure 1.

Figure 1.

DXP synthase catalyzes the ThDP-dependent formation of DXP, which is an intermediate in thee essential bacterial biosynthesis pathways. E = DXPS. R = 4′-amino-2-methyl-5-pyrimidyl. R′ = β-hydroxyethyldiphosphate.