| Progression‐free survival | ||||||
| Study | Groups (N =, E = ) | Median (weeks) | 95% CI | P value | Hazard Ratio (95% CI) | |
| Meier 2009 | Stratum 1 | Topotecan (N = 136, E = 127) | 18.1 | 12.7 ‐ 21.0 | 0.0476 | 1.43 (95% CI 1.12 ‐ 1.83) |
| Treosulfan (N = 138, E = 135) | 9.4 | 8.9 ‐ 11.0 | ||||
| Stratum 2 | Topotecan (N = 136, E = 127) | 28.9 | 26.1 ‐ 33.6 | 0.0163 | 1.44 (95% CI 1.00 ‐ 2.07) | |
| Treosulfan (N = 138, E = 135) | 21.4 | 15.0 ‐ 25.3 | ||||
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