Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 15;68(8):1635–1648. doi: 10.2337/db18-1178

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

PMC Copyright notice

AGGF1 dramatically improves essential functions of EPCs impaired by HG. A: Western blot analysis showing increased AGGF1 expression in EPCs. B: AGGF1 treatment reversed the impairment of angiogenic function of EPCs by HG. C: Images from panel B were analyzed, quantified, and plotted. D: AGGF1 treatment reversed the reduced cell proliferation of EPCs by HG. E: AGGF1 treatment reversed the HG-impaired TEM of EPCs. F: Images from panel E were quantified and plotted. G: AGGF1 treatment reversed the HG-impaired migration of EPCs in scratch wound migration assays. H: Representative images from EPC migration assays. Data are mean ± SD. **P < 0.01 (n = 6 mice/group).