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AGGF1 activates AKT-Fyn-Nrf2 signaling in EPCs. A and B: Western blot analysis showing the effect of siRNA for AKT (siAKT) and wortmannin on AGGF1-activated phosphorylation of AKT (p-AKT) and n-Fyn. C–E: Western blot analysis showing the effect of siAKT, wortmannin, and siRNA for Nrf2 (siNrf2) on AGGF1-induced increases of n-Nrf2 and its downstream signaling molecules. Data are mean ± SD. *P < 0.05, **P < 0.01 (n = 3/group). t-AKT, total AKT.
