Skip to main content
. 2019 Dec 4;8:e49305. doi: 10.7554/eLife.49305

Table 1. Curation of the Arabidopsis core model from Arnold and Nikoloski (2014).

Arabidopsis core model Observation one-cell model Reference
NADP-dependent malate dehydrogenases in all compartments cycles through nitrate reductase to interconvert NAD and NADP NAD-dependent malate dehydrogenases in all compartments, NADP-dependent malate dehydrogenase only in chloroplast (Swarbreck et al., 2008)
Cyclic electron flow absence of cyclic electron flow added (Shikanai, 2016)
Alternative oxidase missing alternative routes for electrons to pass the electron transport chain to reduce oxygen added alternative oxidase reactions to the chloroplast and mitochondria (Vishwakarma et al., 2015)
Alanine transferase No alanine transferase in cytosol Alanine transferase added (Liepman and Olsen, 2003)
Transport chloroplast no maltose transporter by MEX1 added (Linka and Weber, 2010)
no glucose transporter by MEX1 and pGlcT MEX1 added
no unidirectional transport of ATP, ADP, AMP by BT-like added
no Mal/OAA, Mal/Pyr, and Mal/Glu exchange by DiTs added
no folate transporter by FBT and FOLT1 added
Transport Mitochondria no Mal/OAA, Cit/iCit, Mal/KG exchange by DTC added (Linka and Weber, 2010)
no H+ importer by UCPs import added
no OAA/Pi exchange by DIC1-3 added
no ATP/Pi exchange by APCs added
no NAD/ADP and NAD/AMP exchange by NDT2 added
no ThPP/ATP exchange by TPCs added
no Asp/Glu by AGCs added
no uncoupled Ala exchange added
Transport peroxisome missing NAD/NADH, NAD/ADP, NAD/AMP exchange by PXN added (Linka and Weber, 2010)
no ATP/ADP and ATP/AMP exchange by PNCs added
H+ sinks/sources H+ sinks/source reaction for the cytosol and futile transport cycles introduced by H+ -coupled transport reactions H+ sinks/source reaction added for each compartment
ATPase stoichiometry False H+/ATP ratios for the plastidal and mitochondrial ATP synthase H+/ATP ratio set to 3 : 1 (chloroplast) and 4:1 (mitochondria) (Petersen et al., 2012; Turina et al., 2016)
Alanine/aspartate transferase no direct conversion of alanine and aspartate added to cytosol, chloroplast and mitochondria (Schultz and Coruzzi, 1995; Duff et al., 2012)