REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Rabbit anti-mCherry (#AB167453)	Abcam	RRID:AB_2571870
Rabbit anti-GluR2/3 (#AB1506)	Millipore	RRID:AB_90710
Chicken anti-GFP (#AB13970)	Abcam	RRID:AB_300798
Rabbit anti-somatostatin (#T4103)	Peninsula Laboratories	RRID:AB_518614
Alexa 568 Goat Anti-Rabbit (#A11036)	Invitrogen	RRID:AB_10563566
Alexa 488 Goat Anti-Chicken (#A11039)	Invitrogen	RRID:AB_142924
FluoroJade B	Histo-Chem	Cat#1 FJB
Hoechst 33442 Trihydrochloride, Trihydrate	Thermofisher	Cat#H 1399
Bacterial and Virus Strains
AAV2-hSyn-DIO-hM4D(Gi)-mCherry	Addgene	Cat#44362; RRID:Addgene_44362
AAV2-EF1 α-DIO-hChR2(H134R)-eYFP	University of North Carolina Vector Core	N/A
AAV2-EF1 α-DIO-eYFP	University of North Caroline Vector Core	N/A
AAV2-hSyn-DIO-hM3D(Gq)-mCherry	Addgene	Cat#44361; RRID:Addgene_44361
Chemicals, Peptides, and Recombinant Proteins
Pilocarpine Hydrochloride	Sigma	Cat#P6503
Scopolamine Methyl Nitrate	Sigma	Cat#S2250
Terbutaline Hemisulfate	Sigma	Cat#T2528
Ethosuximide	Sigma	Cat#E7138
Diazepam	Hospira	NDC #0409–3213-12
Bicuculline Methiodide (BMI)	Sigma	Cat#14343
CGP52432	Sigma	Cat#SML0593
4-Aminopyridine (4-AP)	Sigma	Cat#A0152
Clozapine N-Oxide (CNO)	Enzo Life Sciences	Cat#BML-NS105–0005
DL-APV	Sigma	Cat#A5282
DCG-IV	Tocris	Cat#0975
DNQX	Tocris	Cat#0189
Deposited Data
Raw and analyzed data	This paper; Mendeley Data	http://dx.doi.org/10.17632/m8jpfctxmy.2
Experimental Models: Organisms/Strains
Mouse: DrD2-Cre (C57BL/6N)	Dr. Emmanuel Valjent	N/A
Mouse: C57BL/6N (stock #027)	Charles River	RRID:IMSR_CRL:027
Software and Algorithms
Sirenia Acquisition	Pinnacle Technology	RRID:SCR_016183
Sirenia Seizure	Pinnacle Technology	RRID:SCR_016184
Spike2	Cambridge Electronic Design	RRID:SCR_00903
Clampfit	Molecular Devices	RRID:SCR_011323
pClamp	Molecular Devices	RRID:SCR_011323
Prism	GraphPad	RRID:SCR_002798
G*Power	G*Power	RRID:SCR_013726
ImageJ	NIH	RRID:SCR_003070
Adobe Photoshop	Adobe	RRID:SCR_014199
Inkscape	Inkscape	RRID:SCR 014479