Table 1. Demographics and characteristics of the patients in this study.
| Parameters | Total | Study group | Validation group |
|---|---|---|---|
| Patients, n | 36 | 31 | 5 |
| Age (years) | 45.2 ± 14.9 | 44.8 ± 14.9 | 49.8 ± 15.3 |
| Male/female, n | 21/15 | 18/13 | 3/2 |
| Weight (kg) | 55.0 ± 14.5 | 55.6 ± 11.3 | 49.9 ± 26.2 |
| BMI (kg/m2) | 20.8 ± 14.5 | 21.0 ± 3.0 | 19.4± 9.1 |
| ABO compatible/incompatible, n | 29/7 | 27/4 | 2/3 |
| Virus infection, n | |||
| CMV | 1 | 1 | 0 |
| VZV | 1 | 1 | 0 |
| Acute rejection, n | 2 | 2 | 0 |
| Total AUC measurements, n | 96 | 79 | 17 |
| Serum creatinine (mg/dl) | 1.25 ± 0.37 | 1.26 ± 0.33 | 1.20 ± 0.53 |
| Serum K (mEq/l) | 4.43 ± 0.52 | 4.47 ± 0.54 | 4.22 ± 0.40 |
| Hemoglobin (g/dl)a | 11.0 ± 1.77 | 10.9 ± 1.76 | 11.3 ± 182 |
| Hematocrit (%)b | 33.5 ± 5.26 | 33.2 ± 5.21 | 34.6 ± 5.52 |
| Dose of tacrolimus (mg/kg) | 0.113 ± 0.041 | 0.116 ± 0.039 | 0.101 ± 0.052 |
| Trough of tacrolimus (ng/ml) | 6.61 ± 3.01 | 6.46 ± 2.67 | 7.33 ± 4.30 |
| AUC (ng/ml) | 162.9 ± 52.8 | 162.7 ± 50.9 | 163.7 ± 61.7 |
number or mean ± SD. SD, standard deviation; BMI, body mass index; CMV, cytomegalovirus; VZV, varicella zoster virus; AUC, area under the curve.
an = 78.
bn = 77.