. 2019 Nov 19;8:e48901. doi: 10.7554/eLife.48901

Table 1. Measures of support (using differences in the corrected Akaike information criterion, AICc - AICc_min; see Materials and methods) for models in which CD4⁺ T_CM derive directly from CD4⁺ naive T cells, and T_EM derive either from naive T cells or T_CM.

AICc differences are shown in bold, with zero indicating the model with strongest support, and positive differences representing reduced support, with differences of 10 or more generally considered highly significant. Figures in parentheses are the log likelihoods, reflecting the quality of fit of each model. We also show the number of parameters estimated for each model in each environment.

		CD4⁺ central memory	CD4⁺ effector memory
		Source population	Source population
Model	Parameters	CD4⁺ naive	CD4⁺ naive	CD4⁺ central memory
Homogeneous	3	128 (10)	89 (75)	160 (39)
Two-phase	5	9 (74)	29 (109)	0 (124)
Age-dependent loss	4	0 (76)	29 (107)	10 (117)
Resistant memory	4	26 (63)	45 (99)	49 (97)

Table 1. Measures of support (using differences in the corrected Akaike information criterion, AICc - AICcmin; see Materials and methods) for models in which CD4+ TCM derive directly from CD4+ naive T cells, and TEM derive either from naive T cells or TCM.

Table 1. Measures of support (using differences in the corrected Akaike information criterion, AICc - AICc_min; see Materials and methods) for models in which CD4⁺ T_CM derive directly from CD4⁺ naive T cells, and T_EM derive either from naive T cells or T_CM.