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. 2019 Dec 11;5(12):eaax7331. doi: 10.1126/sciadv.aax7331

Fig. 2. Antemortem sleep fragmentation and expression of aging-associated microglial genes—Participants with and without AD pathology.

Fig. 2

Samples with (A) low or no and (B) intermediate or high NIA-Reagan AD classification. Partial residual plot of microglial gene expression summary score as a function of antemortem sleep fragmentation adjusted for age, sex, education, and methodological covariates. Y axis is the composite expression for the gene set calculated as described in the text. X axis is average antemortem sleep fragmentation. Each dot represents a single sample. Solid line indicates the predicted composite gene expression for an average participant. Dotted lines indicate 95% CIs on the prediction.