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. 2019 Dec 5;10:1478. doi: 10.3389/fphar.2019.01478

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Copyright © 2019 Fan, Ding, Lan, Niu, He and Song

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Potential anti-inflammatory action of FGF-1 in DIO mice. (A–B) Plasma concentrations of pro-inflammatory cytokines TNF-α (A) and IL-6 (B) in ND, HFD, and HFD+FGF-1 group. (C) Relative mRNA levels of hepatic inflammation-related gene expression in liver tissues of ND, HFD, and HFD+FGF-1. (D) Western blot analysis of total liver lysates from ND, HFD, and HFD+FGF-1 groups. Error bars denote SEM. Statistical analysis was performed by ANOVA followed by Tukey in (A–D). *P < 0.05; **P < 0.01. Uncropped blots can be found in Supplementary Figure 5.