Table 4.
The predictive value indices for predicting in-hospital adverse outcomes in clinically useful scoring systems
| Score | Youden index | Cut-off | SEN | 95%CI | SPE | 95%CI | PPV | 95%CI | NPV | 95%CI |
| In-hospital rebleeding | ||||||||||
| CTP | 0.3851 | > 7 | 74.6 | 62.5-84.5 | 63.9 | 57.8-69.7 | 34.5 | 29.8-39.4 | 90.8 | 86.6-93.8 |
| CRS | 0.3982 | > 2 | 65.7 | 53.1-76.8 | 74.1 | 68.4-79.3 | 39.3 | 33.1-45.8 | 89.4 | 85.8-92.2 |
| In-hospital mortality | ||||||||||
| CRS | 0.6751 | > 2 | 94.3 | 80.8-99.3 | 73.2 | 67.8-78.2 | 29.5 | 25.4-33.9 | 99.1 | 96.6-99.8 |
| CTP | 0.5632 | > 7 | 94.3 | 80.8-99.3 | 62.0 | 56.2-67.6 | 22.8 | 20.0-25.8 | 98.9 | 96.0-99.7 |
| AIMS65 | 0.6339 | > 1 | 80.0 | 63.1-91.6 | 83.4 | 78.6-87.5 | 36.4 | 29.6-43.7 | 97.2 | 94.8-98.6 |
| MELD-Na | 0.5685 | > 17 | 71.4 | 53.7-85.4 | 85.4 | 80.9-89.2 | 36.8 | 29.1-45.1 | 96.2 | 93.7-97.7 |
| MELD | 0.5157 | > 12 | 74.3 | 56.7-87.5 | 77.3 | 72.1-81.9 | 28.0 | 22.6-34.1 | 96.2 | 93.5-97.8 |
| mGBS | 0.4349 | > 10 | 68.6 | 50.7-83.1 | 74.9 | 69.6-79.8 | 24.5 | 19.4-30.4 | 95.3 | 92.5-97.1 |
| CANUKA | 0.3521 | > 12 | 45.7 | 28.8-63.4 | 89.5 | 85.4-92.7 | 34.0 | 24.0-45.8 | 93.3 | 91.1-95.0 |
| GBS | 0.3700 | > 12 | 74.3 | 56.7-87.5 | 62.7 | 56.9-68.2 | 19.1 | 15.6-23.2 | 95.4 | 92.1-97.3 |
| In-hospital adverse outcomes | ||||||||||
| CTP | 0.4699 | > 7 | 78.8 | 68.6-86.9 | 68.2 | 61.9-73.9 | 46.2 | 41.0-51.5 | 90.3 | 85.9-93.4 |
| CRS | 0.5095 | > 2 | 71.8 | 61.0-81.0 | 79.2 | 73.6-84.1 | 54.5 | 47.5-61.2 | 89.0 | 85.1-91.9 |
| MELD-Na | 0.3758 | > 13 | 69.4 | 58.5-79.0 | 68.2 | 61.9-73.9 | 43.1 | 37.5-48.8 | 86.5 | 82.2-89.9 |
| MELD | 0.3241 | > 13 | 45.9 | 35.0-57.0 | 86.5 | 81.6-90.5 | 54.2 | 44.4-63.6 | 82.2 | 79.0-84.9 |
| AIMS65 | 0.3830 | > 1 | 51.8 | 40.7-62.7 | 86.5 | 81.6-90.5 | 57.1 | 47.7-66.1 | 83.8 | 80.5-86.6 |
SEN: Sensitivity; SPE: Specificity; PPV: Positive predictive value; NPV: Negative predictive value; CI: Confidence interval; CTP: Child-Turcotte-Pugh score; MELD: Model for end-stage liver disease; CRS: Clinical Rockall score; GBS: Glasgow-Blatchford score; mGBS: Modified Glasgow-Blatchford score; AIMS65: AIMS65 score; CANUKA: Canada-United Kingdom-Australia score.