Table 4.
Correlation between absolute change in lumbar spine BMD and preoperative levels of markers of bone metabolism; R: Spearman correlation index
| Placebo group | Strontium group | |||
|---|---|---|---|---|
| Spearman index (R) | p | Spearman index (R) | p | |
| Age | 0.085 | 0.706 | 0.139 | 0.473 |
| PTH | 0.292 | 0.187 | 0.232 | 0.226 |
| Ca++ | 0.292 | 0.187 | 0.256 | 0.180 |
| OC | 0.634 | 0.002 | 0.352 | 0.061 |
| P1NP | 0.750 | < 0.001 | 0.413 | 0.029 |
| CTX | 0.634 | 0.002 | 0.274 | 0.159 |
| BAP | 0.229 | 0.413 | 0.488 | 0.029 |
| OPG | − 0.116 | 0.627 | − 0.162 | 0.450 |
| RANKL | 0.600 | 0.400 | − 0.800 | 0.200 |
| SOST | 0.098 | 0.682 | 0.079 | 0.713 |
| DKK-1 | − 0.030 | 0.904 | − 0.206 | 0.335 |
BMD bone mineral density, PTH parathyroid hormone, Ca++ ionized calcium, OC osteocalcin, P1NP procollagen type 1 N-terminal propeptide, CTX CrossLaps, BAP bone-specific alkaline phosphatase, OPG osteoprotegerin, RANKL receptor activator of nuclear factor-kappa ligand, SOST sclerostin, DKK-1 Dickkopf-1