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. 2019 Dec 11;9:18907. doi: 10.1038/s41598-019-55329-x

Figure 1.

Figure 1

Noise treatment causes a decrease in τbound in both sensory and supporting cells of the organ of Corti. (A) Schematic of the organ of Corti, showing the four cell types investigated in this work. (B) NAD(P)H fluorescence intensity images of cochlea preparations from three week old (P21–23) mice exposed to mild (TTS) noise treatment (2 hours at 100 dB SPL) compared to control (unexposed) conditions (scale bar 10 µm). (C) Mean enzyme bound NAD(P)H fluorescence lifetimes of each cell type (*P < 10−4). (D) FLIM images colour coded to the mean τbound value in each cellular region of interest.