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. 2019 Dec 11;9:18885. doi: 10.1038/s41598-019-55363-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cardiovascular parameters during development of obesity. The analysis of cardiovascular parameters began in 30^th of life of mouse and repeated every 10 days until 70^th of life, using the Coda Platform. The mean arterial pressure (A) was expressed in millimeters of mercury (mmHg) and the heart rate (B) was expressed in beats per minute. Data show mean ± SEM. ****p < 0.0001 when compared control group vs obese group. The number of animals used was: 30 control and 23 obese mice.