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. 2019 Dec 11;9:18885. doi: 10.1038/s41598-019-55363-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Obesity modulate nitric oxide production. The nitric oxide (NO) was estimated by production of nitrite through cadmium/Griess technique and was measured in plasma (A), aorta (B), heart tissue (C) and adipose tissue from retroperitoneal region (D) on 13^th day post infection. The levels of NO were expressed in NO micromolar (NO²µM). Bars represent mean ± SEM of eight mice per group. *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001 when compared between groups.