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. 2019 Dec 11;9:18870. doi: 10.1038/s41598-019-54716-8

Table 3.

Synergistic activity of tridecaptin M in the presence of efflux pump inhibitors.

Strain Intrinsic Activity; MIC (µg/ml) MIC (µg/ml) of Tri-M in the presence of EPIs FICI
PAβN CCCP CCCP
Tri-M PAβN CCCP 1/4th MIC 1/8th MIC 1/4th MIC 1/8th MIC 1/4th MIC 1/8th MIC
A. baumannii ATCC 19606 64 64 64 64 64 4 8 0.31 0.25
P. aeruginosa ATCC 27853 256 64 64 256 256 256 256
K. pneumoniae ATCC 700603 2 256 128 2 2 2 2
K. pneumoniae P3R (Tri-M Resistant) 64 256 128 64 64 64 64
K. pneumoniae GMCH 13 8 256 32 8 8 4 8 0.75
K. pneumoniae GMCH 15 16 256 64 16 16 4 8 0.5 0.62

Tri-M= Tridecaptin M (or M1).