Table 2.
Correlation between arylsulfatase A expression and pathological aspects of colorectal cancer
| Characteristics | Number |
ARSA expression |
P value | |
| Low | High | |||
| Age, yr | ||||
| ≤ 60 | 19 | 8 | 11 | 0.761 |
| > 60 | 26 | 13 | 13 | |
| Gender | ||||
| Male | 26 | 12 | 14 | > 0.991 |
| Female | 19 | 9 | 10 | |
| Macroscopic aspect | ||||
| Polypoid | 12 | 9 | 3 | 0.041 |
| Ulcero-infiltrative | 33 | 12 | 21 | |
| Microscopic aspect | ||||
| G1 | 14 | 11 | 3 | 0.022 |
| G2 | 24 | 9 | 15 | |
| G3+4 | 7 | 2 | 5 | |
| Localization | ||||
| Proximal | 8 | 5 | 3 | 0.502 |
| Distal | 21 | 10 | 11 | |
| Upper rectum | 16 | 6 | 10 | |
| Lymph node ratio | ||||
| < 0.1 | 34 | 19 | 15 | 0.041 |
| ≥ 0.1 | 11 | 2 | 9 | |
| Lymph node metastasis | ||||
| Absent | 29 | 17 | 12 | 0.031 |
| Present | 16 | 4 | 12 | |
| pT stage | ||||
| ≤ T2 | 15 | 3 | 12 | 0.011 |
| ≥ T3 | 30 | 18 | 12 | |
| Budding grade | ||||
| G1 | 15 | 8 | 7 | 0.812 |
| G2 | 9 | 4 | 5 | |
| G3 | 21 | 9 | 12 | |
| Maspin expression | ||||
| Positive | 22 | 3 | 19 | < 0.00011 |
| Negative | 23 | 18 | 5 | |
| ARSB expression | ||||
| Low | 11 | 5 | 6 | 0.921 |
| High | 34 | 16 | 18 | |
1
Fisher’s exact test.
2
χ2 test. Significant differences are shown in bold. G1: Well differentiated; G2: Moderately differentiated; G3: Poorly differentiated, 4 mucinous.