Mental state: 4. Average score (various scales, high = poor)) (skewed data)
Study	Intervention	Mean	SD	N
Depressive symptoms ‐ 3 months (BDI‐11)
Baker 2006	Treatment	16.93	12.51	58
Baker 2006	Control	10.93	10.43	61
Depressive symptoms ‐ 6 months (BDI‐11)
Baker 2006	Treatment	14.10	11.38	58
Baker 2006	Control	9.92	9.29	61
Depressive symptoms ‐ 12 months (BDI‐11)
Baker 2006	Treatment	17.14	13.20	44
Baker 2006	Control	9.68	10.30	53
Depressive symptoms ‐ 3 months Calgary Depression Scale
Madigan 2013	Treatment	4.4	4.3	40
Madigan 2013	Control	4.6	4.8	20
Depressive symptoms ‐ 12 months Calgary Depression Scale
Madigan 2013	Treatment	4.3	4.4	33
Madigan 2013	Control	4.3	4.2	11
General symptoms total score ‐ 6 months (BPRS)
Baker 2006	Treatment	35.47	9.34	58
Baker 2006	Control	34.52	8.53	61
General symptoms total score ‐ 12 months (BPRS)
Baker 2006	Treatment	35.43	8.59	44
Baker 2006	Control	32.58	8.19	53
General symptoms total score ‐ 3 months (BPRS)
Baker 2006	Treatment	35.31	9.04	58
Baker 2006	Control	34.46	11.24	61
General symptoms ‐ 18 months (PANSS)
Barrowclough 2001	Treatment	21.13	6.39	15
Barrowclough 2001	Control	30.07	8.17	14
Barrowclough 2014	Treatment (long)	35.1	9.0	23
Barrowclough 2014	Control	31.6	8.5	21
Total score ‐ 3 months (PANSS)
Gouzoulis‐Mayfrank 2015	Treatment	65.36	28.26	50
Gouzoulis‐Mayfrank 2015	Control	77.42	31.55	50
Total score ‐ 6 months (PANSS)
Gouzoulis‐Mayfrank 2015	Treatment	61.92	26.823	50
Gouzoulis‐Mayfrank 2015	Control	77.9	33.254	50
Total score ‐ 12 months (PANSS)
Barrowclough 2001	Treatment	56.88	14.23	17
Barrowclough 2001	Control	63.40	17.96	15
Total score ‐ 18 months (PANSS)
Barrowclough 2001	Treatment	52.20	11.12	15
Barrowclough 2001	Control	58.50	15.04	14
Manic symptoms ‐ 3 months (BPRS)
Baker 2006	Treatment	6.43	2.46	58
Baker 2006	Control	7.39	3.51	61
Manic symptoms ‐ 6 months (BPRS)
Baker 2006	Treatment	6.38	2.23	58
Baker 2006	Control	6.57	3.56	61
Manic symptoms ‐ 12 months (BPRS)
Baker 2006	Treatment	6.07	1.63	44
Baker 2006	Control	6.18	2.32	53
Negative symptoms ‐ 3 months (BPRS)
Baker 2006	Treatment	6.24	2.10	58
Baker 2006	Control	6.48	2.47	61
Negative symptoms ‐ 6 months (BPRS)
Baker 2006	Treatment	6.00	1.52	58
Baker 2006	Control	6.08	1.54	61
Negative symptoms ‐ 12 months (BPRS)
Baker 2006	Treatment	6.86	1.36	44
Baker 2006	Control	6.58	2.35	53
Negative symptoms ‐ 6 months (PANSS)
Hjorthoj 2013	Treatment	16.3	5.92	34
Hjorthoj 2013	Control	15.3	5.35	28
Negative symptoms ‐ 9‐10 months (PANSS)
Barrowclough 2001	Treatment	12.47	4.12	17
Barrowclough 2001	Control	16.20	4.87	15
Hjorthoj 2013	Treatment	14.9	5.2	34
Hjorthoj 2013	Control	15.2	6.15	26
Negative symptoms ‐ 12 months (PANSS)
Barrowclough 2001	Treatment	12.65	4.97	17
Barrowclough 2001	Control	14.67	6.02	15
Negative symptoms ‐ 18 months (PANSS)
Barrowclough 2001	Treatment	10.27	2.25	15
Barrowclough 2001	Control	15.50	5.71	14
Barrowclough 2014	Treatment	13.7	3.9	23
Barrowclough 2014	Control	15.2	6.5	21
Negative symptoms ‐ 3 months (SANS)
Madigan 2013	Treatment	3.8	2.4	40
Madigan 2013	Control	3.2	2.3	20
Negative symptoms ‐ 12 months (SANS)
Madigan 2013	Treatment	4.6	3	32
Madigan 2013	Control	4.8	3.2	19
Positive symptoms ‐ 6 months (PANSS)
Hjorthoj 2013	Treatment	15.6	5.09	34
Hjorthoj 2013	Control	17	5.01	28
Positive symptoms ‐ 9‐10 months (PANSS)
Barrowclough 2001	Treatment	15.29	4.69	17
Barrowclough 2001	Control	16.40	4.29	15
Hjorthoj 2013	Treatment	14.4	5.22	34
Hjorthoj 2013	Control	16.2	4.99	26
Positive symptoms ‐ 12 months (PANSS)
Barrowclough 2001	Treatment	13.35	4.57	17
Barrowclough 2001	Control	16.07	5.54	15
Positive symptoms ‐ 18 months (PANSS)
Barrowclough 2001	Treatment	13.87	4.27	15
Barrowclough 2001	Control	12.93	4.23	14
Barrowclough 2014	Treatment (Long)	13.0	4.6	24
Barrowclough 2014	Control	12.7	5.1	21
Positive symptoms ‐ 3 months (SAPS)
Madigan 2013	Treatment	4.8	3.7	42
Madigan 2013	Control	5.1	4.1	22
Positive symptoms ‐ 12 months (SAPS)
Madigan 2013	Treatment	4.9	4	32
Madigan 2013	Control	5.1	4.2	17