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. 2019 Dec 12;2019(12):CD001088. doi: 10.1002/14651858.CD001088.pub4

Bechdolf 2011.

Methods Allocation: randomised.
 Design: single‐centre.
 Duration: 6 months.
 Setting: Inpatient, some of the treatment could be as outpatient.
Location: Cologne, Germany.
Participants Diagnosis: ICD‐10 schizophrenia or schizoaffective disorder (n = 50, 83.3%) or substance‐induced psychosis (n = 10) with substance abuse or dependence.
 N = 60.
 Age: mean 31.5 years.
 Sex: 43 M, 17 F.
 Ethnicity: not reported.
 Inclusion criteria: German speaking and excluded if they were close to discharge.
Interventions 1. Psychosocial intervention: MI (4 individual sessions of 50 minutes each given as an inpatient) plus routine care. N = 30.
 2. Standard care: routine care plus 4 sessions of non‐specific supportive sessions (Supportive Therapy, ST). N = 30.
Outcomes Leaving the study early: lost to evaluation (3 and 6 months).
Unable to use
Mental state: PANSS (no means or SDs reported).
Global state: GAF (no means or SDs reported).
Substance use: ASI alcohol, cannabis consumption (skewed data).
Service use: relapse (hospitalisations) (not reported).
Notes All analyses were performed by intention‐to‐treat conditions.
Text was translated from German to English by internal translators.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Stratified for gender and SUD, single and multiple. Sequence generation not stated.
Allocation concealment (selection bias) Unclear risk Researcher not involved in the study generated sequence. Insufficient information to permit judgement.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Clinician‐/participant‐mediated and participants and personnel not blinded. It is not possible to blind a psychosocial intervention.
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Raters blinded so detection bias was rated as low.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Lost to follow‐up: 25% (15/60) 6 months.
Missing data have been imputed using appropriate methods (LOCF), but these can still have unclear risk effects.
Selective reporting (reporting bias) Unclear risk Rating of mental state not fully reported (numerical data not provided for PANSS, GAF) both secondary outcomes reported as not significantly different between groups over time.
Other bias Low risk None according to authors.