Bond 1991a.
Methods | Allocation: randomised.
Design: single‐centre (two sites, see Bond‐Evansville).
Duration: 18 months.
Setting: community centre. Location: Anderson, SC, USA. |
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Participants | Diagnosis: 57% DSM‐III‐R schizophrenia with co‐occurring substance disorder. N = 42.* Age: 18 ‐ 45 years, mean ˜ 30 years. Sex: 14 M, 7 F (only 21 received treatment). Ethnicity: 14% black. Inclusion criteria: chronic, DSM‐III‐R or documented evidence of substance abuse / dependence, extensive hospital/crisis service use over previous year. | |
Interventions | 1. Psychosocial intervention: non‐integrated ACT. Includes reference groups to encourage attendance at CMHC'S, peer support group meetings several times/week, not focused exclusively on substance abuse, used successful members as role models, also home and community visits throughout project period. N = 21. 2. Standard care: routine care. N = 21.** | |
Outcomes | Leaving the study early: lost to treatment. No other usable data (57% lost to follow‐up). | |
Notes | ITT analysis. * Control group same as Bond‐Evansville 91. Only 21 received treatment (all figures given are for those 21 who received treatment). ** 4 received assistance from a case management program. Authors have kindly provided further data. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomised, no further details. |
Allocation concealment (selection bias) | Unclear risk | No details. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Clinician‐/participant‐mediated and participants and personnel not blinded. It is not possible to blind a psychosocial intervention. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Unclear if raters were blind. |
Incomplete outcome data (attrition bias) All outcomes | High risk | Lost to follow‐up: 57% (24/42 18 months and 50% (21/42) did not receive treatment as planned and no reasons given for missing or lost to follow‐up. |
Selective reporting (reporting bias) | Unclear risk | No protocol to compare outcomes reported. In the published auricles, means and SD were not reported, but were kindly provided by the author. |
Other bias | Low risk | No evidence other biases are occurring. |