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. 2019 Dec 12;2019(12):CD001088. doi: 10.1002/14651858.CD001088.pub4

Kemp 2007.

Methods Allocation: randomised.
 Design: single‐centre.
 Duration: 6 months.
 Setting: community based early intervention programme.
Location: Western Sydney, NSW, Australia.
Participants Diagnosis: DSM‐IV psychotic illness and current alcohol or cannabis use based on AUDIT or DAST scores.
 N = 19.
 Age: mean ˜ 21 years, range 17‐25 years.
 Sex: 13 M, 3 F (3, Unknown).
Ethnicity: not stated.
 Inclusion criteria: young English speaking, living within the area health sector and not homeless.
Interventions 1. Psychosocial intervention: MI + CBT, Stop using stuff (SUS) manualised 4‐6 hours. N = 10.
2. Standard care: TAU, standard care included case management and has a significant focus on substance reduction. N = 9.
Outcomes Leaving the study early: lost to evaluation.
Mental state: PANSS total.
Unable to use
Mental State: DASS (some data skewed).
Substance use: AUDIT, DAST‐10 frequency and quantity of cannabis or alcohol use (skewed data).
Notes Authors have kindly provided additional data.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Randomised, cards were shuffled, numbered and placed in sealed envelopes.
Allocation concealment (selection bias) Unclear risk Numbered sealed envelopes with the allocation placed into a box by a third person. Envelopes were then drawn in order from the box each time a patient was randomised. Unclear whether envelopes were opaque.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Clinician‐/participant‐mediated and participants and personnel not blinded. It is not possible to blind a psychosocial intervention.
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Measures that were clinician‐rated were all performed by the clinician providing the treatment and were therefore not blinded.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Lost to follow‐up: 16% (3/19) 6 months. Three patients dropped out of the TAU group, no explanation was given. No ITT analysis.
Selective reporting (reporting bias) Unclear risk Insufficient information to permit judgement of 'yes' or 'no' as no protocol was available.
Other bias Unclear risk Had extreme baseline imbalance in substance use (AUDIT), DASS and self‐efficacy score. This could be due to low subject numbers recruited for study.