Table 2.
Summary of the effects of silibinin on mitochondrial parameters in HepG2 and PC12 cells.
| Respiration | Basal MMP/+SNP | Basal ATP/+SNP | Citrate synthase activity | Glycolysis | |
|---|---|---|---|---|---|
| HepG2 | ↑ | ↑/↑ | ↑↑/↑ | ↔ | ↓ |
| PC12 | ↔ | ↔/↑↑ | ↑/↑↑ | ↔ | ↔ |
↑ indicates an increase, ↓ indicates a reduction, and ↔ indicates no change. SNP = sodium nitroprusside.