Figure 1.
Membrane levels of KCa2.3 and KCa3.1 are altered in NP and PE. (a) PM levels of KCa2.3 and KCa3.1 in ECs treated with NNP or NP serum. (b) PM levels of KCa2.3 and KCa3.1 in ECs treated with NP or PE serum. (c, d) PM levels of KCa2.3 (c) and KCa3.1 (d) in ECs treated with CM, NNP serum, NP serum, or PE serum. (e) PM levels of KCa2.3 or KCa3.1 in ECs treated with oxidized LDL. Reduced KCa2.3 or KCa3.1 levels were reversed by blocking oxidized LDL receptor using an anti-LOX1 Ab. Blots shown are representative of the three to five experiments performed with three to five different cultures. Bar graphs represent the mean ± SEM. ∗P < 0.05, ∗∗P < 0.01.