Figure 2.

Distributions of Patient Health Questionnaire-4 (PHQ) and derived measures for depressive symptoms. (A) Density plot for all 4 time points of assessment for PHQ. Instance = 2 was for imaging assessment, and the depressive level acquired from this instance was used as a baseline one-time measure for depressive symptoms. The mean depressive level over a minimum of 2 time points of assessment (Depre.mean) is also presented in this panel. (B) Density plot for instability of depressive symptoms (Depre.variability). (C) Density plot for the distribution of slope for the longitudinal trajectory of depressive level over 4 instances (Depre.longitudinal). The density plots were made using the geom_density function in ggplot2 with a smoothness adjustment of 2.