Table 6.
Correlations between serum chemerin and visfatin with parameters of pulmonary involvement in SSc patients with use of Spearman’s rank correlation test
| Parameter of pulmonary involvement | Chemerin | Visfatin | ||||
|---|---|---|---|---|---|---|
| Total SSc group | lcSSc | dcSSc | Total SSc group | lcSSc | dcSSc | |
| Presence of ILD |
r = –0.155 p = 0.301 |
r = 0.160 p = 0.322 |
N/A* |
r = 0.089 p = 0.554 |
r = 0.086 p = 0.596 |
N/A* |
| %DLCO |
r = 0.212 p = 0.297 |
r = 0.107 p = 0.632 |
r = 0.4 p = 0.6 |
r = –0.09 p = 0.660 |
r = –0.158 p = 0.481 |
r = 0.8 p = 0.2 |
| %FVC |
r = 0.241 p = 0.127 |
r = 0.215 p = 0.205 |
r = 0.1 p = 0.872 |
r = 0.034 p = 0.832 |
r = –0.07 p = 0.666 |
r = 0.7 p = 0.188 |
| RVSP |
r = –0.04 p = 0.79 |
r = 0.08 p = 0.621 |
r = –0.82 p = 0.041 |
r = 0.143 p = 0.339 |
r = 0.194 p = 0.229 |
r = –0.207 p = 0.693 |
| Early/mid–stage SSc | Late SSc | Early/mid–stage SSc | Late SSc | |||
| Presence of ILD |
r = –0.410 p = 0.272 |
r = –0.313 p = 0.058 |
r = 0.41 p = 0.272 |
r = 0.033 p = 0.843 |
||
| %DLCO | N/A** |
r = 0.178 p = 0.404 |
N/A ** |
r = 0.05 p = 0.814 |
||
| %FVC |
r = –0.542 p = 0.265 |
r = 0.422 p = 0.011 |
r = –0.6 p = 0.208 |
r = 0. 114 p = 0.512 |
||
| RVSP |
r = 0.125 p = 0.766 |
r = –0.059 p = 0.723 |
r = 0.755 p = 0.03 |
r = 0.025 p = 0.879 |
||
*
All patients with dcSSc had ILD on HRCT.
**
Only 2 patients with early/mid-stage disease had estimated %DLCO, lcSSc – limited cutaneous systemic sclerosis, dcSSc – diffuse cutaneous systemic sclerosis, ILD – interstitial lung disease, DLCO – diffusing capacity for carbon monoxide, FVC – forced vital capacity, TLC – total lung capacity, RVSP – right ventricular systolic pressure.