Table 1.

Clinical trials in SCI with neurophysiological outcome measures (CONT.)

	Year	Study design	Population	Sample size	Intervention	Comparison	Outcome of interest
Frolov et al62	2012	Pre-post	Chronic SCI	N=20	Hematopoietic autologous stem cell	NA	MEPs, SSEPs
Trumbower et al63	2012	Pre-post	Chronic SCI AIS C-D	N=13	Acute intermittent hypoxia	NA	EMG
Kumru et al40	2012	RCT	Chronic SCI AIS A-D + healthy controls	N=52	tDCS + visual illusion	None	CHEPs
				(I=18, SCI C=20, healthy C=14)
Mazzoleni et al64	2011	Controlled trial	Chronic SCI AIS C-D & healthy controls	N=10	Locomotor training in SCI	Locomotor training in controls	EMG
				(I= 5, C=5)
Chang et al24	2011	Controlled trial	Chronic SCI AIS A & healthy controls	N=11	Limb segment vibration in SCI	Limb segment vibration in controls	H-reflex
				(I= 5, C=6)
Houldin et al65	2011	Controlled trial	Chronic SCI AIS D + healthy controls	N=26	Lokomat training	No training or Lokomat training	EMG
				(SCI= 9, C=17)
Kuppuswamy et al17	2011	Randomized crossover trial	Chronic SCI AIS A-D	N=15	rTMS	Sham rTMS	MEPs, silent period, SSR
Theiss et al31	2011	Randomized crossover	Chronic SCI AIS C-D	N=7	Riluzole	Control	Flexion reflex, H-reflex
Murillo et al33	2011	Controlled trial	Subacute and chronic SCI AIS A, C, D	N=28	Vibration of rectus femoris in SCI	Vibration of rectus femoris in controls	H-reflex, T wave
				(I=19, C=9)
Adams et al66	2011	Randomized crossover design	Chronic SCI AIS A-C	N=7	BWSTT	Tilt table standing	H-reflex
Grijalva et al67	2010	RCT+ crossover trial	Chronic SCI AIS A	N=14	4 amino pyridine	Placebo	SSEPs
Hoffman et al15	2010	RCT	Chronic SCI AIS B-D	N=13	Bimanual MP + SS	Unimanual MP + SS	MEPs
				(I= 7, C=6)
Kumru et al30	2010	RCT + crossover	Chronic SCI AIS C-D	N=14	rTMS	Sham stim	Flexion reflex, H-reflex, T reflex
				(I= 8, C=7)
Lima et al68	2009	Pre-post	Chronic SCI AIS A-B	N=20	Olfactory mucosal cells	NA	EMG, SSEPs
Chhabra et al38	2009	Pre-post	Chronic SCI AIS A-B	N=5	Autologous olfactory mucosal transplantation	NA	EMG, MEPs, NCS, SSEPs,
Cotey et al69	2009	Controlled trial	Chronic SCI AIS A, B, C + healthy controls	N=16	Lokomat gait training + vibration to quads in SCI	Lokomat gait training + vibration to quads in healthy controls	EMG
				(SCI=11, healthy C= 5)
Cristante et al70	2009	Pre-post	Chronic SCI	N=39	Stem cells	NA	SSEPs
Gorassini et al71	2009	Controlled trial	Chronic SCI AIS C-D + healthy controls	N=25	BWSTT in SCI	BWSTT in controls	EMG
				(SCI=19, healthy C=6)
Adel et al72	2009	Controlled trial	Chronic SCI AIS A, B, C	N=63	Bone marrow stromal stem cells	No stem cells	SSEPs
				(I=43, C=20)