Table 4.

Multivariable Cox regression analyses predicting cancer-specific survival

	All stage	T1	T2	T3	T4
	Multivariable a HR (95% CI)	Multivariable b HR (95% CI)	Multivariable b HR (95% CI)	Multivariable b HR (95% CI)	Multivariable b HR (95% CI)
LND status
No LND	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)
LND	0.81 (0.73–0.95)**	0.84 (0.56–1.25)	0.87 (0.61–1.24)	0.83 (0.73–0.98)*	0.64 (0.47–0.88)**
LND extent
No LND	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)
Limited LND	0.86 (0.75–0.96)*	1.02 (0.65–1.59)	1.02 (0.69–1.51)	0.92 (0.78–1.16)	0.61 (0.43–0.87)**
Extended LND	0.73 (0.61–0.88)**	0.56 (0.29–1.08)	0.65 (0.38–1.12)	0.74 (0.58–0.95)*	0.70 (0.47–0.96)*
Lymph node stage
pN0	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)	1.00 (Ref.)
pNx	1.32 (1.13–1.53)***	1.29 (0.85–1.98)	1.19 (0.83–1.72)	1.22 (1.01–1.49)*	1.97 (1.31–2.97)**
pN1–3	2.49 (2.06–3.01)***	3.40 (1.61–7.18)**	3.35 (1.87–5.99)***	2.32 (1.81–2.98)***	2.55 (1.64–3.98)***

*P < 0.05, **P < 0.01, ***P < 0.001. ^a Adjusted to age, gender, race, tumor location, laterality, tumor size, tumor stage, tumor grade, chemotherapy and year of surgery. ^b Adjusted to age, gender, race, tumor location, laterality, tumor size, tumor grade, chemotherapy and year of surgery. HR hazard ratio, 95% CI 95% confidence interval, LND lymph node dissection