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The top 10 most used R groups from approved drugs
| R group | SMILES | Occurrence (%) | Both top 10 |
|---|---|---|---|
| Methyl | *C | 23.6 | O |
| Hydroxy | *O | 18.2 | O |
| Chloro | *Cl | 6.4 | O |
| Amino | *N | 5.1 | |
| Methoxy | *OC | 5.0 | O |
| Carboxy | *C(=O)O | 3.9 | O |
| Fluoro | *F | 2.9 | O |
| Ethyl | *CC | 2.2 | |
| Hydroxymethyl | *CO | 1.7 | |
| Trifulromethyl | *C(F)(F)F | 1.0 | O |
