Table 2.

Effects of pioglitazone on metabolic parameters

Variables	CTRL	LD	PIO-L	PIO-H	EZE
Body weight (g)	479.39 ± 50.97	511.83 ± 70.00	490.13 ± 40.78	435.46 ± 69.62*	492.46 ± 63.29
Blood glucose (mmol/L)	3.35 ± 0.52	3.90 ± 0.63	3.39 ± 0.68	2.99 ± 0.39**	3.43 ± 0.51
Insulin (mmol/L)	2.45 ± 0.53	3.00 ± 0.54	2.58 ± 0.59	2.40 ± 0.53*	2.51 ± 0.29
CH (mmol/L)	3.60 ± 0.74**	6.28 ± 0.91	5.85 ± 0.77	5.04 ± 1.07*	4.36 ± 0.81**
TG (mmol/L)	0.37 ± 0.07**	0.63 ± 0.10	0.50 ± 0.10*	0.44 ± 0.10**	0.47 ± 0.09**
LDL-C(mmol/L)	1.39 ± 0.19**	2.02 ± 0.30	1.84 ± 0.27	1.72 ± 0.27*	1.64 ± 0.18*
HDL-C (mmol/L)	1.03 ± 0.20**	0.69 ± 0.19	0.77 ± 0.14	0.91 ± 0.10*	0.94 ± 0.18*

Values are expressed as means ± SD (n = 8). ^∗P < 0.05 and ^∗∗P < 0.01 versus LD