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. 2019 Dec 11;10:46. doi: 10.1186/s13229-019-0301-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Global patterns of normative brain maturation for diffusion (FA, ADC) and anatomical (surface area, volume, thickness) metrics. Note that the brain parcellation used for anatomical metrics included only cortical GM. Heterogeneous effects of age on diffusion metrics are observed across tissue types. All anatomical metrics decline with age, with a similar trend in both hemispheres