Table 3.
Thromboelastography on preoperatively , postoperative day 1, 4, and 7
| Topical-TXA(n = 72) | IV-TXA (n = 68) | Control(n = 67) | ||
|---|---|---|---|---|
| Items | Mean ± SD | Mean ± SD | Mean ± SD | p value |
| R (min) | ||||
| Preoperatively | 6.6 ± 0.7 | 6.6 ± 0.8 | 6.8 ± 0.7 | 0.247 |
| Postoperative | ||||
| Day 1 | 5.7 ± 0.8$* | 4.9 ± 0.9# | 6.0 ± 0.7 | 0.000 |
| Day 4 | 5.4 ± 0.6$ | 4.6 ± 0.8# | 5.6 ± 0.6 | 0.000 |
| Day 7 | 6.1 ± 0.7$ | 5.5 ± 0.8# | 6.1 ± 0.7 | 0.000 |
| K (min) | ||||
| Preoperatively | 3.5 ± 1.0 | 3.5 ± 0.9 | 3.5 ± 0.7 | 0.904 |
| Postoperative | ||||
| Day 1 | 2.4 ± 0.7$ | 2.0 ± 0.8# | 2.6 ± 0.7 | 0.000 |
| Day 4 | 2.2 ± 0.7$ | 1.7 ± 0.7# | 2.3 ± 0.7 | 0.000 |
| Day 7 | 2.7 ± 0.7$ | 2.0 ± 0.7# | 2.8 ± 0.7 | 0.000 |
| MA (mm) | ||||
| Preoperatively | 61.5 ± 8.4 | 61.3 ± 6.9 | 61.4 ± 9.1 | 0.989 |
| Postoperative | ||||
| Day 1 | 64.5 ± 8.1 | 66.1 ± 6.8# | 62.1 ± 9.2 | 0.017 |
| Day 4 | 67.4± ± 8.0$ | 70.2 ± 6.1# | 66.1 ± 9.1 | 0.010 |
| Day 7 | 70.4 ± 4.1 | 70.9 ± 4.6 | 70.9 ± 4.1 | 0.695 |
| α (°) | ||||
| Preoperatively | 55.4 ± 11.4 | 55.2 ± 12.3 | 55.5 ± 16.5 | 0.988 |
| Postoperative | ||||
| Day 1 | 62.1 ± 11.4 | 66.3 ± 12.7 | 61.7 ± 16.6 | 0.092 |
| Day 4 | 71.5 ± 10.8$ | 77.6 ± 10.9# | 70.6 ± 15.2 | 0.002 |
| Day 7 | 66.4 ± 11.6$ | 72.4 ± 12.5# | 64.9 ± 16.6 | 0.004 |
| CI | ||||
| Preoperatively | 0.4 ± 1.0 | 0.5 ± 0.9 | 0.4 ± 0.9 | 0.803 |
| Postoperative | ||||
| Day 1 | 1.4 ± 1.1$ | 2.0 ± 0.8# | 1.4 ± 0.9 | 0.000 |
| Day 4 | 2.3 ± 1.1$ | 2.9 ± 0.9# | 2.3 ± 0.9 | 0.001 |
| Day 7 | 1.4 ± 1.2$ | 2.0 ± 0.8# | 1.4 ± 0.9 | 0.000 |
$Significant difference (p < 0.05) between topical-TXA and IV-TXA groups
*Significant difference (p < 0.05) between topical-TXA and control groups
#Significant difference (p < 0.05) between IV-TXA and control groups