Table 5.

Pathway analysis (top ten) of downregulated genes of the intestine of laying hens in LP group relative to PP group¹ (n = 4)

Pathway name	Ko_ID	Richment _factor	P-value	Q-value
PPAR signaling pathway	ko03320	11.7	< 0.001	0.002
Oxidative phosphorylation	ko00190	8.3	< 0.001	0.003
Glutathione metabolism	ko00480	13.2	< 0.001	0.009
Drug metabolism - cytochrome P450	ko00982	13.1	0.001	0.059
Metabolism of xenobiotics by cytochrome P450	ko00980	12.4	0.002	0.068
Glycine, serine and threonine metabolism	ko00260	11.8	0.002	0.079
Carbon metabolism	ko01200	5.5	0.006	0.222
Glyoxylate and dicarboxylate metabolism	ko00630	10.7	0.015	0.583
Renal cell carcinoma	ko05211	53.7	0.018	0.740
Circadian rhythm	ko04710	40.3	0.025	0.984

¹PP laying hens in the peak phase of production, LP laying hens in the late phase of production