Table 1.
– Patient characteristics at enrolment (safety population, n = 1293)
| Indication | Pretreatment | Total, n (%) | Male, n (%) | Female, n (%) | Mean age (± SD) years | Mean BMI (± SD)a kg/m2 |
|---|---|---|---|---|---|---|
| Isolated GHD | Naïve | 94 (7.3) | 39 (3.0) | 55 (4.3) | 46.9 (15.4) | 29.7 (6.6) |
| Pretreated | 61 (4.7) | 27 (2.1) | 34 (2.6) | 42.7 (16.2) | 31.3 (8.8) | |
| MPHD | Naïve | 537 (41.5) | 289 (22.4) | 248 (19.2) | 49.5 (14.7) | 29.7 (6.3) |
| Pretreated | 591 (45.7) | 305 (23.6) | 286 (22.1) | 50.4 (15.6) | 29.0 (6.2) | |
| Other | Naïve | 6 (0.5) | 4 (0.3) | 2 (0.2) | 44.9 (13.1) | 29.0 (0.6) |
| Pretreated | 4 (0.3) | 2 (0.2) | 2 (0.2) | 31.7 (9.1) | 26.0 (5.7) | |
| Total | 1293 (100.0) | 666 (51.5) | 627 (48.5) | 49.3 (15.3) | 29.4 (6.4) |
BMI body mass index; GHD growth hormone deficiency; MPHD multiple pituitary hormone deficiency; SD standard deviation
an = 1092 patients with BMI recorded at enrolment