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. 2019 Dec 11;19:361. doi: 10.1186/s12906-019-2776-1

Table 4.

IC50 values of inhibition towards beta-hexosaminidase and histamine release

IC50 values of inhibition
Beta-hexosaminidase Histamine
M. oleifera leaf extract 7.17 ± 1.69 μg/mL** 11.66 ± 1.26 μg/mL
M. oleifera seed extract 10.68 ± 0.63 μg/mL 5.97 ± 0.84 μg/mL
M. oleifera pod extract 14.89 ± 1.25 μg/mL 7.43 ± 1.01 μg/mL
Ethyl-(E)–undec-6-enoate (1) 82.68 ± 1.98 μM 82.07 ± 13.75 μM
3,5,6-trihydroxy-2-(2,3,4,5,6-pentahydroxyphenyl)-4H-chromen-4-one (2) 17.70 ± 23.29 μM 44.87 ± 2.13 μM
Quercetin (3) 19.07 ± 7.19 μM* 7.77 ± 27.86 μM
Kaempferol (4) 29.39 ± 6.26 μM 46.94 ± 10.26 μM
β-sitosterol-3-O-glucoside (5) 24.93 ± 2.10 μM
Oleic acid (6) 53.76 ± 8.95 μM 56.05 ± 37.11 μM
Glucomoringin (7) 10.43 ± 1.51 μM* 27.22 ± 18.62 μM
Stigmasterol (9) 75.92 ± 4.66 μM 38.27 ± 24.48 μM
Ketotifen fumarate (positive control)

15.19 ± 1.10 μg/mL

(35.70 ± 2.59 μM)

6.97 ± 0.04 μg/mL

(16.38 ± 0.10 μM)