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. 2019 Dec 12;9:32. doi: 10.1186/s13395-019-0218-x

Table 2.

Validated hits from hSSPN-EGFP screen reveal enrichment of calcium channel blockers

Compound Description
Felodipine L-type Ca2 + channel blocker
GW5074 cRaf1 kinase inhibitor
Isoproterenol Sympathomimetic amine acting on β-adrenoceptors
Isradipine L-type Ca2 + channel blocker
Lacidipine L-type Ca2 + channel blocker
Nandrolone Anabolic-androgenic steroid
Nilvadipine L-type Ca2 + channel blocker

The screen resulted in 13 initial hits, which were further validated with the hSSPN-EGFP reporter with an n = 24. The 7 validated hits included an overrepresented number of L-type calcium channel blockers